Ledipasvir and sofosbuvir fixed-dose combination with and without ribavirin for 12 weeks in treatment-naive and previously treated Japanese patients with genotype 1 hepatitis C: an open-label, randomised, phase 3 trial

Summary Background Compared with other countries, patients with chronic hepatitis C infection in Japan tend to be older, have more advanced liver disease, and are more likely to have been previously treated for hepatitis C. We aimed to assess the efficacy and safety of an all-oral, fixed-dose combin...

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Veröffentlicht in:The Lancet infectious diseases 2015-06, Vol.15 (6), p.645-653
Hauptverfasser: Mizokami, Masashi, Prof, Yokosuka, Osamu, Prof, Takehara, Tetsuo, Prof, Sakamoto, Naoya, Prof, Korenaga, Masaaki, MD, Mochizuki, Hitoshi, MD, Nakane, Kunio, MD, Enomoto, Hirayuki, MD, Ikeda, Fusao, MD, Yanase, Mikio, MD, Toyoda, Hidenori, MD, Genda, Takuya, MD, Umemura, Takeji, MD, Yatsuhashi, Hiroshi, Prof, Ide, Tatsuya, MD, Toda, Nobuo, MD, Nirei, Kazushige, Ueno, Yoshiyuki, Prof, Nishigaki, Yoichi, MD, Betular, Juan, BS, Gao, Bing, PhD, Ishizaki, Akinobu, BA, Omote, Masa, PhD, Mo, Hongmei, MD, Garrison, Kim, PhD, Pang, Phillip S, MD, Knox, Steven J, BS, Symonds, William T, PharmD, McHutchison, John G, MD, Izumi, Namiki, Prof, Omata, Masao, Prof
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