Dynamic Enhancer Methylation - A Previously Unrecognized Switch for Tissue-Type Plasminogen Activator Expression: e0141805

Tissue-type plasminogen activator (t-PA), which is synthesized in the endothelial cells lining the blood vessel walls, is a key player in the fibrinolytic system protecting the circulation against occluding thrombus formation. Although classical gene regulation has been quite extensively studied in...

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Veröffentlicht in:	PloS one 2015-10, Vol.10 (10)
Hauptverfasser:	Magnusson, Mia, Lu, Emma Xuchun, Larsson, Pia, Ulfhammer, Erik, Bergh, Niklas, Caren, Helena, Jern, Sverker
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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