Effects of lymphocyte profile on development of EBV-induced lymphoma subtypes in humanized mice

Epstein-Barr virus (EBV) infection causes both Hodgkin’s lymphoma (HL) and non-Hodgkin’s lymphoma (NHL). The present study reveals that EBV-induced HL and NHL are intriguingly associated with a repopulated immune cell profile in humanized mice. Newborn immunodeficient NSG mice were engrafted with hu...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2015-10, Vol.112 (42), p.13081-13086
Hauptverfasser:	Lee, Eun Kyung, Joo, Eun Hye, Song, Kyung-A, Choi, Bongkum, Kim, Miyoung, Kim, Seok-Hyung, Kim, Sung Joo, Kang, Myung-Soo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Sciences Epstein-Barr virus Herpesvirus 4, Human - pathogenicity Humans Lymphocytes Lymphocytes - classification Lymphoma Lymphoma, B-Cell - classification Lymphoma, B-Cell - immunology Lymphoma, B-Cell - virology Mice Mice, Inbred NOD Mice, SCID Rodents Stem cells Tumors
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