Lower Serotonin Transporter Binding Potential in the Human Brain During Major Depressive Episodes

OBJECTIVE: CSF analysis, neuroendocrine challenges, serotonin depletion studies, and treatment studies implicate the serotonergic system in the pathophysiology of major depressive disorder. On the basis of postmortem and imaging studies, the authors hypothesized that subjects with major depressive d...

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Veröffentlicht in:The American journal of psychiatry 2006-01, Vol.163 (1), p.52-58
Hauptverfasser: Parsey, Ramin V., Hastings, Ramin S., Oquendo, Maria A., Huang, Yung-yu, Simpson, Norman, Arcement, Julie, Huang, Yiyun, Ogden, R. Todd, Van Heertum, Ronald L., Arango, Victoria, Mann, J. John
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Sprache:eng
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