Doubling Up on Microtubule Stabilizers: Synergistic Functions of Doublecortin-like Kinase and Doublecortin in the Developing Cerebral Cortex
Dynamic regulation of neuronal cytoskeletal machinery in response to extracellular cues enables distinct changes in neuronal development in the cerebral cortex. In this issue of Neuron, three related studies on doublecortin-like kinase, a microtubule-associated protein related to doublecortin, by Sh...
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| Veröffentlicht in: | Neuron (Cambridge, Mass.) Mass.), 2006-01, Vol.49 (1), p.3-4 |
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| container_title | Neuron (Cambridge, Mass.) |
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| creator | Weimer, Jill M. Anton, E.S. |
| description | Dynamic regulation of neuronal cytoskeletal machinery in response to extracellular cues enables distinct changes in neuronal development in the cerebral cortex. In this issue of
Neuron, three related studies on doublecortin-like kinase, a microtubule-associated protein related to doublecortin, by Shu et al., Koizumi et al., and Deuel et al., provide evidence that doublecortin-like kinase is essential for proper neurogenesis, neuronal migration, and axonal wiring. |
| doi_str_mv | 10.1016/j.neuron.2005.12.016 |
| format | Article |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete; Cell Press Free Archives; Free E-Journal (出版社公開部分のみ） |
| subjects | Aging Animals Animals, Newborn - growth & development Animals, Newborn - metabolism Cerebral Cortex - embryology Cerebral Cortex - growth & development Cerebral Cortex - metabolism Drug Synergism Embryo, Mammalian - metabolism Embryo, Nonmammalian Embryonic Development Genes Kinases Microtubule-Associated Proteins - physiology Migration Neurogenesis Neurons Neuropeptides - physiology Protein-Serine-Threonine Kinases - physiology Proteins Rodents Studies |
| title | Doubling Up on Microtubule Stabilizers: Synergistic Functions of Doublecortin-like Kinase and Doublecortin in the Developing Cerebral Cortex |
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