Transiently responsive protein-polymer conjugates viaa 'grafting-from' RAFT approach for intracellular co-delivery of proteins and immune-modulators

We report on transiently responsive protein-polymer conjugates that temporarily change their protein conformation from the soluble to the particle-like state. 'Grafting-from' RAFT polymerization of a dioxolane-containing acrylamide with a protein macroCTA is used to design polymer-protein...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2015-08, Vol.51 (73), p.13972-13975
Hauptverfasser:	Vanparijs, N, De Coen, R, Laplace, D, Louage, B, Maji, S, Lybaert, L, Hoogenboom, R, De Geest, BG
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrylamide Conjugates Diols Grafting Hydrolysis Nanoparticles Proteins Rafts
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!