Divergent synthetic routes to biologically relevant types of compounds: chiral polyfunctional γ-lactams and amino acids

Divergent and versatile synthetic routes leading to the title compounds are described. They start from a common chiral precursor derived from (−)-(S)-verbenone and afford polyfunctional γ-lactams and γ- and ε-amino acids. The cyclobutane moiety in these molecules acts as a chiral and polyfunctional...

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Veröffentlicht in:	Tetrahedron 2014-09, Vol.70 (37), p.6546-6553
Hauptverfasser:	Aguilera, Jordi, Moglioni, Albertina, Mor, Àlex, Ospina, Jimena, Illa, Ona, Ortuño, Rosa M.
Format:	Artikel
Sprache:	eng
Schlagworte:	(−)-(S)-Verbenone Amino acids Asymmetry Carbon Chirality Derivatives Divergent synthesis Functional groups Platforms Polyfunctional scaffolds Precursors Tetrahedrons γ-Lactams
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