Nanostructured substrates for portable and miniature SPR biosensors
Surface plasmon resonance (SPR) biosensing has matured into a valuable analytical technique for measurements related to biomolecules, environmental contaminants, and the food industry. Contemporary SPR instruments are mainly suitable for laboratory-based measurements. However, several point-of-measu...
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Veröffentlicht in: | Analytical and bioanalytical chemistry 2012-06, Vol.403 (6), p.1477-1484 |
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description | Surface plasmon resonance (SPR) biosensing has matured into a valuable analytical technique for measurements related to biomolecules, environmental contaminants, and the food industry. Contemporary SPR instruments are mainly suitable for laboratory-based measurements. However, several point-of-measurement applications would benefit from simple, small, portable and inexpensive sensors to assess the health condition of a patient, potential environmental contamination, or food safety issues. This Trend article explores nanostructured substrates for improving the sensitivity of classical SPR instruments and nanoparticle (NP)-based colorimetric substrates that may provide a solution to the development of point-of-measurement SPR techniques. Novel nanomaterials and methodology capable of enhancing the sensitivity of classical SPR sensors are destined to improve the limits of detection of miniature SPR instruments to the level required for most applications. In a different approach, paper or substrate-based SPR assays based on NPs, are a highly promising topic of research that may facilitate the widespread use of a novel class of miniature and portable SPR instruments.
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Miniature plasmonic sensors based on nano structured substrates |
doi_str_mv | 10.1007/s00216-012-5963-1 |
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Figure
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Figure
Miniature plasmonic sensors based on nano structured substrates</description><subject>Analytical Chemistry</subject><subject>Biochemistry</subject><subject>Biosensing Techniques</subject><subject>Characterization and Evaluation of Materials</subject><subject>Chemistry</subject><subject>Chemistry and Materials Science</subject><subject>Food contamination</subject><subject>Food Science</subject><subject>Foods</subject><subject>Instrument industry</subject><subject>Laboratory Medicine</subject><subject>Mathematical analysis</subject><subject>Medical equipment</subject><subject>Miniature</subject><subject>Miniaturization</subject><subject>Monitoring/Environmental Analysis</subject><subject>Nanocomposites</subject><subject>Nanomaterials</subject><subject>Nanostructure</subject><subject>Nanostructures</subject><subject>Physiological apparatus</subject><subject>Portability</subject><subject>Sensors</subject><subject>Surface Plasmon Resonance - instrumentation</subject><subject>Trends</subject><issn>1618-2642</issn><issn>1618-2650</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkstq3jAQhU1padK0D9BNMXTTjdMZyRrJy_CTXiC0pZe10M3Bwbb-Svaib18Zp4FCaYIWkkbfmSOYU1UvEc4RQL7NAAypAWSN6Ig3-Kg6RULVMBLw-O7cspPqWc43ACgU0tPqhDHBqNRPq8MnM8e8pNUtawq-zqstN7OEXPcx1ceYFmPHUJvZ19MwD2bD6m9fvtZ2iDnMOab8vHrSmzGHF7f7WfXj3eX3w4fm6vP7j4eLq8ZRS0sjLSeHEMiH3lArvXTWCgPABTlJ3Evhre0FcPScQiCS4NGCcGTaIuNn1Zu97zHFn2vIi56G7MI4mjnENWuUbSuRS_VAFBQydj-KElUHhHA_CooxLP7tA1AU0DHFRUFf7-i1GYMe5j6WAbgN1xct65SiTmze5_-gyvJhGlycQz-U-l8C3AUuxZxT6PUxDZNJv4q33uKj9_joEh-9xUdj0by6_fVqp-DvFH_yUgC2A7k8zdch6Zu4prlM_T9dfwPbc8wk</recordid><startdate>20120601</startdate><enddate>20120601</enddate><creator>Breault-Turcot, Julien</creator><creator>Masson, Jean-Francois</creator><general>Springer-Verlag</general><general>Springer</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7QH</scope><scope>7QO</scope><scope>7UA</scope><scope>8FD</scope><scope>C1K</scope><scope>F1W</scope><scope>FR3</scope><scope>H96</scope><scope>H97</scope><scope>L.G</scope><scope>P64</scope><scope>7SR</scope><scope>7U5</scope><scope>8BQ</scope><scope>JG9</scope><scope>L7M</scope></search><sort><creationdate>20120601</creationdate><title>Nanostructured substrates for portable and miniature SPR biosensors</title><author>Breault-Turcot, Julien ; 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Contemporary SPR instruments are mainly suitable for laboratory-based measurements. However, several point-of-measurement applications would benefit from simple, small, portable and inexpensive sensors to assess the health condition of a patient, potential environmental contamination, or food safety issues. This Trend article explores nanostructured substrates for improving the sensitivity of classical SPR instruments and nanoparticle (NP)-based colorimetric substrates that may provide a solution to the development of point-of-measurement SPR techniques. Novel nanomaterials and methodology capable of enhancing the sensitivity of classical SPR sensors are destined to improve the limits of detection of miniature SPR instruments to the level required for most applications. In a different approach, paper or substrate-based SPR assays based on NPs, are a highly promising topic of research that may facilitate the widespread use of a novel class of miniature and portable SPR instruments.
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subjects | Analytical Chemistry Biochemistry Biosensing Techniques Characterization and Evaluation of Materials Chemistry Chemistry and Materials Science Food contamination Food Science Foods Instrument industry Laboratory Medicine Mathematical analysis Medical equipment Miniature Miniaturization Monitoring/Environmental Analysis Nanocomposites Nanomaterials Nanostructure Nanostructures Physiological apparatus Portability Sensors Surface Plasmon Resonance - instrumentation Trends |
title | Nanostructured substrates for portable and miniature SPR biosensors |
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