Nanostructured substrates for portable and miniature SPR biosensors

Surface plasmon resonance (SPR) biosensing has matured into a valuable analytical technique for measurements related to biomolecules, environmental contaminants, and the food industry. Contemporary SPR instruments are mainly suitable for laboratory-based measurements. However, several point-of-measu...

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Veröffentlicht in:Analytical and bioanalytical chemistry 2012-06, Vol.403 (6), p.1477-1484
Hauptverfasser: Breault-Turcot, Julien, Masson, Jean-Francois
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Masson, Jean-Francois
description Surface plasmon resonance (SPR) biosensing has matured into a valuable analytical technique for measurements related to biomolecules, environmental contaminants, and the food industry. Contemporary SPR instruments are mainly suitable for laboratory-based measurements. However, several point-of-measurement applications would benefit from simple, small, portable and inexpensive sensors to assess the health condition of a patient, potential environmental contamination, or food safety issues. This Trend article explores nanostructured substrates for improving the sensitivity of classical SPR instruments and nanoparticle (NP)-based colorimetric substrates that may provide a solution to the development of point-of-measurement SPR techniques. Novel nanomaterials and methodology capable of enhancing the sensitivity of classical SPR sensors are destined to improve the limits of detection of miniature SPR instruments to the level required for most applications. In a different approach, paper or substrate-based SPR assays based on NPs, are a highly promising topic of research that may facilitate the widespread use of a novel class of miniature and portable SPR instruments. Figure Miniature plasmonic sensors based on nano structured substrates
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source MEDLINE; Springer Nature - Complete Springer Journals
subjects Analytical Chemistry
Biochemistry
Biosensing Techniques
Characterization and Evaluation of Materials
Chemistry
Chemistry and Materials Science
Food contamination
Food Science
Foods
Instrument industry
Laboratory Medicine
Mathematical analysis
Medical equipment
Miniature
Miniaturization
Monitoring/Environmental Analysis
Nanocomposites
Nanomaterials
Nanostructure
Nanostructures
Physiological apparatus
Portability
Sensors
Surface Plasmon Resonance - instrumentation
Trends
title Nanostructured substrates for portable and miniature SPR biosensors
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