An InBr3 catalyzed one-pot three-component synthesis of functionalized spirodihydrofuran oxindoles via intramolecular alkyne carbonyl metathesis

A new and convenient one-pot methodology for the reaction of N-methyl isatin, alkynes and phenacyl bromides to selectively afford spiro dihydrofuran oxindole derivatives catalyzed by indium bromide under ambient temperature conditions has been documented. The method has been applied for the synthesi...

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Veröffentlicht in:	Tetrahedron letters 2013-12, Vol.54 (51), p.6991-6994
Hauptverfasser:	Siddiqui, I.R., Rahila, Shamim, Shayna, Rai, Pragati, Shireen, Waseem, Malik A., Abumhdi, Afaf A.H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkyne carbonyl metathesis Alkynes Ambient temperature Bromides Derivatives Dihydrofuran Indium Indium (III) reagents Mathematical analysis One-pot Spirooxindole Synthesis (chemistry) Tetrahedrons
Online-Zugang:	Volltext
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