Sugar-derived cyclic imines: one-pot synthesis and direct functionalization

A simple method for the synthesis of sugar-derived imines by a Schwartz's reagent reduction of easily available sugar lactams has been described. A direct addition of nucleophiles to the generated in situ cyclic imines and subsequent deprotection of hydroxyl function allows to convert sugar lac...

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Veröffentlicht in:	Tetrahedron 2014-03, Vol.70 (10), p.1880-1888
Hauptverfasser:	Szcześniak, Piotr, Stecko, Sebastian, Staszewska-Krajewska, Olga, Furman, Bartłomiej
Format:	Artikel
Sprache:	eng
Schlagworte:	Activation of amides Amides Imines Iminosugars Nucleophiles Piperidine Pyrrolizidines Reduction Sugar-derived lactams Sugars Synthesis Tetrahedrons
Online-Zugang:	Volltext
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