A novel strategy for the synthesis of 2,6-diaryl-1,2-dihydropyridines via 6I-electrocyclization

A novel strategy for the synthesis of 2,6-diaryl-1,2-dihydropyridines via 6I-electrocyclization

Enaminonitriles with I-,I2-unsaturated aldehydes in a BF3ADTOEt2 catalyzed reaction gave stable 1-azatrienes, which could be readily transformed to 1,2-dihydropyridines via 1,6-electrocyclizations.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Tetrahedron 2013-07, Vol.69 (30), p.6269-6274
Hauptverfasser: Vincze, Zoltan, Nemes, Peter
Format: Artikel
Sprache:eng
Schlagworte:
Aldehydes
Strategy
Synthesis
Tetrahedrons
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Enaminonitriles with I-,I2-unsaturated aldehydes in a BF3ADTOEt2 catalyzed reaction gave stable 1-azatrienes, which could be readily transformed to 1,2-dihydropyridines via 1,6-electrocyclizations.
ISSN:0040-4020
DOI:10.1016/j.tet.2013.05.013