Three-component synthesis of 2-amino-3-cyano-5-oxo-4-perfluoroalkyl-5,6,7,8-tetrahydro-4H-chrom e ne derivatives

A variety of 2-amino-3-cyano-5-oxo-4-perfluoroalkyl-5,6,7,8-tetrahydro-4H-chrom e ne derivatives were achieved via a one-pot, three-component reaction from easily available methyl 2-perfluoroalkynoate, malononitrile (or ethyl cyanoacetate), and diverse cyclic 1,3-diketones. Moderate to good yields (...

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Veröffentlicht in:	Tetrahedron 2013-07, Vol.69 (30), p.6121-6128
Hauptverfasser:	Bian, Linglin, Xu, Jiechao, Xie, Liqing, Chen, Jie, Deng, Hongmei, Shao, Min, Ding, Tianling, Zhang, Hui, Cao, Weiguo
Format:	Artikel
Sprache:	eng
Schlagworte:	Catalysis Catalysts Derivatives Malononitrile Synthesis Tetrahedrons
Online-Zugang:	Volltext
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