Asymmetric iridium-catalyzed hydrogenation of 2-methylindole using phosphite ligands

•Ir-catalyzed asymmetric hydrogenation of 2-methylindole.•Use of monodentate phosphite and amidophosphite ligands.•Use of iodine as the additive resulted in increased enantioselectivity. The iridium-catalyzed asymmetric hydrogenation of 2-methylindole using monodentate phosphites and amidophosphites...

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Veröffentlicht in:	Tetrahedron letters 2014-06, Vol.55 (26), p.3613-3614
Hauptverfasser:	Lyubimov, Sergey E., Ozolin, Dmitry V., Davankov, Vadim A.
Format:	Artikel
Sprache:	eng
Schlagworte:	2-Methylindole Additives Asymmetric hydrogenation Asymmetry Catalysts Conversion Hydrogenation Inorganic salts Iridium Ligands Phosphites Tetrahedrons
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