Microwave-mediated synthesis and manipulation of a 2-substituted-5-aminooxazole-4-carbonitrile library

A library of oxazoles is synthesised using parallel synthetic methodology. A 2-substituted-5-aminooxazole-4-carbonitrile library has been synthesised and modified via microwave-mediated and flow chemistries. One synthesised compound, 5-(1H-pyrrol-1-yl)-4-(1H-tetrazol-5-yl)-2-(thien-2-yl)oxazole, con...

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Veröffentlicht in:	Tetrahedron letters 2012-03, Vol.53 (13), p.1656-1659
Hauptverfasser:	Spencer, John, Patel, Hiren, Amin, Jahangir, Callear, Samantha K., Coles, Simon J., Deadman, John J., Furman, Christophe, Mansouri, Roxane, Chavatte, Philippe, Millet, Régis
Format:	Artikel
Sprache:	eng
Schlagworte:	Flow chemistry Libraries Microwave-assisted synthesis Oxazole Oxazoles Parallel synthesis Receptors Synthesis (chemistry) Tetrahedrons
Online-Zugang:	Volltext
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