An efficient green protocol for the synthesis of coumarin fused highly decorated indenodihydropyridyl and dihydropyridyl derivatives

A simple, convenient, environmentally benign, and mild synthetic method has been established to afford highly decorated indenodihydropyridine and dihydropyridine derivatives employing a green solvent ethyl-l-lactate and an organo-catalyst (±)lactic acid. A wide range of functional groups were tolera...

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Veröffentlicht in:Tetrahedron letters 2012-04, Vol.53 (17), p.2206-2210
Hauptverfasser: Paul, Sanjay, Das, Asish R.
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creator Paul, Sanjay
Das, Asish R.
description A simple, convenient, environmentally benign, and mild synthetic method has been established to afford highly decorated indenodihydropyridine and dihydropyridine derivatives employing a green solvent ethyl-l-lactate and an organo-catalyst (±)lactic acid. A wide range of functional groups were tolerated in the developed protocol. The target molecules were obtained in moderate to good yields applying the current method.
doi_str_mv 10.1016/j.tetlet.2012.02.077
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1873-3581
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source Elsevier ScienceDirect Journals Complete
subjects Coumarin
Decoration
Derivatives
Dihydropyridine
Functional groups
Green protocol
Indenodihydropyridine
Organocatalyst
Solvents
Synthesis (chemistry)
Tetrahedrons
title An efficient green protocol for the synthesis of coumarin fused highly decorated indenodihydropyridyl and dihydropyridyl derivatives
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