An efficient green protocol for the synthesis of coumarin fused highly decorated indenodihydropyridyl and dihydropyridyl derivatives
A simple, convenient, environmentally benign, and mild synthetic method has been established to afford highly decorated indenodihydropyridine and dihydropyridine derivatives employing a green solvent ethyl-l-lactate and an organo-catalyst (±)lactic acid. A wide range of functional groups were tolera...
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Veröffentlicht in: | Tetrahedron letters 2012-04, Vol.53 (17), p.2206-2210 |
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Hauptverfasser: | , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | A simple, convenient, environmentally benign, and mild synthetic method has been established to afford highly decorated indenodihydropyridine and dihydropyridine derivatives employing a green solvent ethyl-l-lactate and an organo-catalyst (±)lactic acid. A wide range of functional groups were tolerated in the developed protocol. The target molecules were obtained in moderate to good yields applying the current method. |
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ISSN: | 0040-4039 1873-3581 |
DOI: | 10.1016/j.tetlet.2012.02.077 |