An improved P(V)-N activation strategy for the synthesis of nucleoside diphosphate 6-deoxy-l-sugars

Four nucleoside diphosphate 6-deoxy-l-sugars have been efficiently synthesized by coupling sugar-1-phosphates prepared from the H-phosphonate precursors with nucleoside 5′-phosphoropiperidates in the presence of 4,5-dicyanoimidazole (DCI) as the activator. Compared to the conventional 1H-tetrazole-p...

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Veröffentlicht in:	Tetrahedron 2014-01, Vol.70 (2), p.294-300
Hauptverfasser:	Sun, Qi, Li, Xingjian, Sun, Jian, Gong, Shanshan, Liu, Gang, Liu, Guodong
Format:	Artikel
Sprache:	eng
Schlagworte:	4,5-Dicyanoimidazole Activation Diphosphates H-Phosphonate Joining Nucleoside diphosphate sugar Nucleosides Phosphoropiperidate Precursors Strategy Sugar-1-phosphate Synthesis Tetrahedrons
Online-Zugang:	Volltext
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