Synthesis of indolo[2,3-a]quinolizine and hexahydro-1H-indolizino[8,7-b]indole derivatives by cascade condensation, cyclization, and Pictet–Spengler reaction: an application to the synthesis of (±)-harmicine

Synthesis of indole alkaloid related compounds using Schiff base formation, intramolecular cyclization (or N-alkylation), and Pictet–Spengler reaction as a cascade one pot condensation has been reported. The cascade chemistry has been applied to the synthesis of (±)-harmicine as a key step.

Bibliographische Detailangaben

Veröffentlicht in:	Tetrahedron letters 2012-09, Vol.53 (37), p.5027-5029
Hauptverfasser:	Sanaboina, Chakrapani, Jana, Samaresh, Chidara, Sridhar, Patro, Balaram, Raolji, Gajendrasinh Balvantsinh, Eppakayala, Laxminarayana
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaloids Cascade reaction Cascades Condensing Derivatives Formations Harmicine Indole alkaloid Pictet–Spengler reaction Schiff bases Synthesis (chemistry) Tetrahedrons
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