Microwave-assisted synthesis of 1,3-benzodioxole derivatives from catechol and ketones or aldehydes

An efficient synthetic procedure for the preparation of a diverse library of 1,3-benzodioxoles was developed by applying controlled microwave heating in comparison with currently available conventional heating. Reactions were completed in less than 3h. The isolation of product is simple, the isolate...

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Veröffentlicht in:Tetrahedron letters 2011-08, Vol.52 (34), p.4371-4374
Hauptverfasser: Pingali, Subramanya R.K., Jursic, Branko S.
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Jursic, Branko S.
description An efficient synthetic procedure for the preparation of a diverse library of 1,3-benzodioxoles was developed by applying controlled microwave heating in comparison with currently available conventional heating. Reactions were completed in less than 3h. The isolation of product is simple, the isolated yields are good to excellent, and this method is applicable to large scale production.
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subjects Aldehydes
Benzodioxoles
Carbonyl protection
Catechol protection
Chemistry
Derivatives
Exact sciences and technology
Heating
Heterocyclic compounds
Heterocyclic compounds with o, s, se, te hetero atom and condensed derivatives
Ketones
Libraries
Microwave-assisted reactions
Microwaves
Noncondensed benzenic compounds
Organic chemistry
Preparations and properties
Synthesis (chemistry)
Tetrahedrons
title Microwave-assisted synthesis of 1,3-benzodioxole derivatives from catechol and ketones or aldehydes
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