Redox-active and Catalytic-efficient PAMAM Dendrimer Nanostructures for Sensing Low-abundance Protein with Signal Amplification

Redox-active and Catalytic-efficient PAMAM Dendrimer Nanostructures for Sensing Low-abundance Protein with Signal Amplification

Functionalized poly(amido amine) (PAMAM) dendrimer nanostructures with redox activity and catalytic ability were for the first time utilized as detectable signal tags for highly efficiency electrochemical immunosensing of low-abundance protein (prostate-specific antigen, PSA, used as a model) on a d...

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Veröffentlicht in:Chemistry letters 2013-08, Vol.42 (8), p.841-842
Hauptverfasser: Pei, Xiaomei, Xu, Zonghui, Zhang, Jiayu, Liu, Zhe, Tian, Jinnian
Format: Artikel
Sprache:eng
Schlagworte:
Amplification
Antigens
Catalysis
Dendrimers
Nanostructure
Proteins
Strategy
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Zusammenfassung:Functionalized poly(amido amine) (PAMAM) dendrimer nanostructures with redox activity and catalytic ability were for the first time utilized as detectable signal tags for highly efficiency electrochemical immunosensing of low-abundance protein (prostate-specific antigen, PSA, used as a model) on a disposable immunosensor, based on an in situ amplification strategy of bioelectrocatalytic reaction.
ISSN:0366-7022
1348-0715
DOI:10.1246/cl.130278