One-pot synthesis of highly diversified tetrahydropyridines by tandem condensation of aldehydes, amines, and β-ketoesters

Silica-supported boron trifluoride (BF3·SiO2) was used as an efficient and reusable catalyst for the synthesis of highly diversified tetrahydropyridines by one-pot multicomponent reactions of amines and aldehydes with β-ketoester. This method proceeds through the intermolecular Mannich reaction foll...

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Veröffentlicht in:	Tetrahedron 2012-01, Vol.68 (1), p.363-369
Hauptverfasser:	Ramachandran, Rajamanickam, Jayanthi, Sampathkumar, Jeong, Yeon Tae
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldehydes Amines Catalysis Catalysts: preparations and properties Chemistry Diffraction Exact sciences and technology General and physical chemistry Graphs Heterocyclic compounds Heterocyclic compounds with only one n hetero atom and condensed derivatives Hydrogen bonding One-pot synthesis Organic chemistry Preparations and properties Silica-supported boron trifluoride Synthesis (chemistry) Tandem reaction Tetrahedrons Tetrahydropyridines Theory of reactions, general kinetics. Catalysis. Nomenclature, chemical documentation, computer chemistry X-rays
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