Stereoselective total synthesis of achaetolide and reconfirmation of its absolute configuration

The stereoselective total synthesis of achaetolide 1 has been achieved and its absolute stereochemistry has been reconfirmed to be 3 S,6 R,7 S,9 R configuration. Keck allylation, Sharpless asymmetric dihydroxylation, and ring closing metathesis are the key steps involved in the target synthesis.

Bibliographische Detailangaben

Veröffentlicht in:	Tetrahedron letters 2010-11, Vol.51 (47), p.6174-6176
Hauptverfasser:	Srihari, P., Kumaraswamy, B., Shankar, P., Ravishashidhar, V., Yadav, J.S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Allyl compounds Asymmetry Austenitic stainless steels Chemical reactions Metathesis Stereochemistry Synthesis (chemistry) Tetrahedrons
Online-Zugang:	Volltext
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