H95 Is a pH-Dependent Gate in Aquaporin 4

Aquaporin 4 (AQP4) is a transmembrane protein from the aquaporin family and is the predominant water channel in the mammalian brain. The regulation of permeability of this protein could be of potential therapeutic use to treat various forms of damage to the nervous tissue. In this work, based on dat...

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Veröffentlicht in:	Structure (London) 2015-12, Vol.23 (12), p.2309-2318
Hauptverfasser:	Kaptan, Shreyas, Assentoft, Mette, Schneider, Hans Peter, Fenton, Robert A., Deitmer, Joachim W., MacAulay, Nanna, de Groot, Bert L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Aquaporin 4 - chemistry Aquaporin 4 - metabolism Histidine - chemistry Humans Hydrogen-Ion Concentration Ion Channel Gating Molecular Sequence Data Oocytes
Online-Zugang:	Volltext
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