Differential involvement of sympathetic nervous system and immune system in the modulation of TNF- alpha production by alpha sub(2)- and beta -adrenoceptors in mice

In the present study, the regulation of tumor necrosis factor- alpha (TNF- alpha ) production by alpha sub(2)- and beta -adrenoceptors located on noradrenergic nerve terminals and on macrophages was studied in endotoxaemic mice. We found that reduction of the sympathetic outflow by reserpine dramati...

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Veröffentlicht in:Journal of neuroimmunology 2000-02, Vol.103 (1), p.34-40
Hauptverfasser: Szelenyi, J, Kiss, J P, Vizi, E S
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Sprache:eng
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