An aroA Mutant of Edwardsiella ictaluri Is Safe and Efficacious as a Live, Attenuated Vaccine

The aroA gene of Edwardsiella ictaluri was cloned and sequenced, and the sequence data were used to construct a deletion–insertion mutation in the aroA gene. The mutated gene was transferred into a virulent, wild‐type E. ictaluri strain by conjugation and allelic exchange. Putative aroA mutants were...

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Veröffentlicht in:Journal of aquatic animal health 1999-12, Vol.11 (4), p.358-372
Hauptverfasser: Thune, Ronald L., Fernandez, Denise H., Battista, John R.
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Sprache:eng
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