Role of redox potential and reactive oxygen species in stress signaling: Stress signaling

Stress-activated signaling cascades are affected by altered redox potential. Key contributors to altered redox potential are reactive oxygen species (ROS) which are formed, in most cases, by exogenous genotoxic agents including irradiation, inflammatory cytokines and chemical carcinogens. ROS and al...

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Veröffentlicht in:	Oncogene 1999-11, Vol.18 (45), p.6104-6111
Hauptverfasser:	ADLER, V, ZHIMIN YIN, TEW, K. D, RONAI, Z
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Carcinogens Cell physiology Cellular stress response Cytokines External stimuli Fundamental and applied biological sciences. Psychology Gene Expression Regulation Genotoxicity Glutathione transferase Glutathione Transferase - metabolism Humans Inflammation Kinases Molecular and cellular biology Oxidation-Reduction Oxidative Stress - physiology Protein kinase Protein Kinases - genetics Protein Kinases - metabolism Radiation Reactive oxygen species Reactive Oxygen Species - metabolism Redox potential Signal Transduction Thioredoxin Thioredoxins - metabolism Transcription factors Transcription Factors - genetics Transcription Factors - metabolism
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