Heterotrimeric G Protein-independent Signaling of a G Protein-coupled Receptor: DIRECT BINDING OF ARNO/CYTOHESIN-2 TO THE CARBOXYL TERMINUS OF THE A sub(2A) ADENOSINE RECEPTOR IS NECESSARY FOR SUSTAINED ACTIVATION OF THE ERK/MAP KINASE PATHWAY
The A sub(2A) adenosine receptor is a prototypical G sub(s)-coupled receptor, but it also signals, e.g. to mitogen-activated protein (MAP) kinase, via a pathway that is independent of heterotrimeric G proteins. Truncation of the carboxyl terminus affects the strength of the signal through these alte...
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Veröffentlicht in: | The Journal of biological chemistry 2005-09, Vol.280 (36), p.31898-31905 |
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Hauptverfasser: | , , , , , |
Format: | Artikel |
Sprache: | eng |
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