Biphasic effect of cadmium in non-cytotoxic conditions on the secretion of nitric oxide from peritoneal macrophages

The effects of cadmium (Cd) in non-cytotoxic conditions on the nitric oxide (NO) production in peritoneal macrophages (pM) were studied. Peritoneal macrophages from Balb/c mice were incubated over 18 h with 5, 10, 20, or 25 μM Cd 2+ (as CdCl 2 21:2 H 2O) in the culture medium. Concentrations of 20 μ...

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Veröffentlicht in:	Toxicology (Amsterdam) 1999-11, Vol.139 (1), p.167-177
Hauptverfasser:	Ramirez, Dario C., Martinez, Luis D., Marchevsky, Eduardo, Gimenez, Maria S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blotting, Western Cadmium Cadmium - toxicity Cell Separation Cell Survival - drug effects Chemical and industrial products toxicology. Toxic occupational diseases Coloring Agents In Vitro Techniques Lipid Peroxidation - drug effects Lipoperoxidation Macrophages Macrophages, Peritoneal - drug effects Macrophages, Peritoneal - metabolism Male Medical sciences Metals and various inorganic compounds Mice Mice, Inbred BALB C Nitric oxide Nitric Oxide - metabolism Nitric oxide synthase Nitric Oxide Synthase - metabolism Nitric Oxide Synthase Type II peritoneum Tetrazolium Salts Thiazoles Thiobarbituric Acid Reactive Substances - metabolism Toxicology
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