The functional polymorphism in the matrix metalloproteinase-7 promoter increases susceptibility to esophageal squamous cell carcinoma, gastric cardiac adenocarcinoma and non-small cell lung carcinoma

An A to G transition at the 181 base pair position upstream of the transcription initiation site of the matrix metalloproteinase-7 (MMP-7) gene (−181A/G) may modify the development and progression of some diseases via influencing the transcription activity of the promoter. To assess the effects of t...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Carcinogenesis (New York) 2005-10, Vol.26 (10), p.1748-1753
Hauptverfasser:	Zhang, Jianhui, Jin, Xia, Fang, Shumei, Wang, Rui, Li, Yan, Wang, Na, Guo, Wei, Wang, Yimin, Wen, Denggui, Wei, Lizhen, Dong, Zhiming, Kuang, Gang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - genetics Biological and medical sciences Carcinogenesis, carcinogens and anticarcinogens Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Squamous Cell - genetics ESCC Esophageal Neoplasms - genetics esophageal squamous cell carcinoma gastric cardiac adenocarcinoma GCA Genetic Predisposition to Disease Heart Neoplasms - genetics Humans Lung Neoplasms - genetics matrix metalloproteinase Matrix Metalloproteinase 7 - genetics Medical sciences MMP non-small cell lung carcinoma NSCLC PCR–RFLP polymerase chain reaction–restriction fragment length polymorphism Polymorphism, Single Nucleotide Promoter Regions, Genetic single nucleotide polymorphism SNP Stomach Neoplasms - genetics Tumors UGIC upper gastrointestinal cancers
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!