Valosin-Containing Protein Phosphorylation at Ser super(784) in Response to DNA Damage

The response of eukaryotic cells to DNA damage includes the activation of phosphatidylinositol-3 kinase-related kinases (PIKK), such as ATM, ATR, and DNA-dependent protein kinase (DNA-PK). These three kinases have very similar substrate specificities in vitro, but in vivo, their substrates overlap o...

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Veröffentlicht in:Cancer research (Chicago, Ill.) Ill.), 2005-09, Vol.65 (17), p.7533-7540
Hauptverfasser: Livingstone, Mark, Ruan, Hong, Weiner, Jessica, Clauser, Karl R, Strack, Peter, Jin, Shengfang, Williams, Amy, Greulich, Heidi, Gardner, James, Venere, Monica, Mochan, Tamara A, DiTullio, Richard AJr, Moravcevic, Katarina, Gorgoulis, Vassilis G, Burkhardt, Anne, Halazonetis, Thanos D
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Sprache:eng
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