Human Immunodeficiency Virus Nef Induces Rapid Internalization of the T-Cell Coreceptor CD8 alpha beta

Human immunodeficiency virus (HIV) Nef is a membrane-associated protein decreasing surface expression of CD4, CD28, and major histocompatibility complex class I on infected cells. We report that Nef strongly down-modulates surface expression of the beta -chain of the CD8 alpha beta receptor by accel...

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Veröffentlicht in:	Journal of virology 2005-09, Vol.79 (17), p.11422-11433
Hauptverfasser:	Stove, Veronique, Van de Walle, Inge, Naessens, Evelien, Coene, Elisabeth, Stove, Christophe, Plum, Jean, Verhasselt, Bruno
Format:	Artikel
Sprache:	eng
Schlagworte:	Human immunodeficiency virus 1 Human immunodeficiency virus 2 Simian immunodeficiency virus
Online-Zugang:	Volltext
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