Immunochemotherapy for Leishmania donovani infection in golden hamsters: combinatorial action of poly ICLC plus L-arginine and sodium stibogluconate (Stibanate)

We demonstrate that golden hamsters infected with Leishmania donovani amastigotes develop the capacity to eliminate intracellular pathogens on treatment with low-dose standard antileishmanial sodium stibogluconate (Stibanate) in combination with polyinosinic-polycytidilic acid stabilized with polyly...

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Veröffentlicht in:	Journal of interferon & cytokine research 1999-10, Vol.19 (10), p.1103-1106
Hauptverfasser:	Bhakuni, V, Kulkarni, S, Ali, V, Singh, U K, Levy, H B, Maheshwari, R K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antimony Sodium Gluconate - therapeutic use Carboxymethylcellulose Sodium - analogs & derivatives Carboxymethylcellulose Sodium - therapeutic use Combined Modality Therapy Cricetinae Dose-Response Relationship, Drug Immunotherapy - methods Interferon Inducers - therapeutic use L-arginine Leishmania donovani Leishmaniasis, Visceral - therapy Male Mesocricetus Poly I-C - therapeutic use poly ICLC Polylysine - analogs & derivatives Polylysine - therapeutic use sodium stibogluconate
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