Toxicology of protein allergenicity: prediction and characterization

The ability of exogenous proteins to cause respiratory and gastrointestinal allergy, and sometimes systemic anaphylactic reactions, is well known. What is not clear however, are the properties that confer on proteins the ability to induce allergic sensitization. With an expansion in the use of enzym...

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Veröffentlicht in:	Toxicological sciences 1999-04, Vol.48 (2), p.157-162
Hauptverfasser:	KIMBER, I, KERKVLIET, N. I, TAYLOR, S. L, ASTWOOD, J. D, SARLO, K, DEARMAN, R. J
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergens - chemistry Allergens - toxicity Biological and medical sciences Experimental and animal immunopathology. Animal models Gastrointestinal Diseases - etiology Immunopathology Medical sciences Plants, Genetically Modified - adverse effects Proteins - immunology Respiratory Hypersensitivity - etiology Risk Assessment Structure-Activity Relationship
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