Protofibril Formation of Amyloid β-Protein at Low pH via a Non-cooperative Elongation Mechanism

Deposition of the amyloid β-protein (Aβ) in senile or diffuse plaques is a distinctive feature of Alzheimer's disease. The role of Aβ aggregates in the etiology of the disease is still controversial. The formation of linear aggregates, known as amyloid fibrils, has been proposed as the onset an...

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