Teratology of retinoids

Either an excess or a deficiency of vitamin A and related compounds (retinoids) causes abnormal morphological development (teratogenesis). Potential retinoid sources come from dietary intake, nutritional supplements, and some therapeutic drugs. Therefore, understanding the mechanisms of retinoid ter...

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Veröffentlicht in:	Annual review of pharmacology and toxicology 1999-01, Vol.39 (1), p.399-430
Hauptverfasser:	Collins, M D, Mao, G E
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities, Drug-Induced - etiology Abnormalities, Drug-Induced - genetics Abnormalities, Drug-Induced - pathology Animals Embryonic and Fetal Development - genetics Female Humans Pregnancy Receptors, Retinoic Acid - drug effects Receptors, Retinoic Acid - genetics retinoids Retinoids - metabolism Retinoids - pharmacokinetics Retinoids - toxicity Teratogens - metabolism Teratogens - pharmacokinetics Teratogens - toxicity
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