Administration of green tea or caffeine enhances the disappearance of UVB-induced patches of mutant p53 positive epidermal cells in SKH-1 mice

Irradiation of female SKH-1 hairless mice with UVB (30 mJ/cm2) twice a week for 10–20 weeks resulted in the formation of a large number of cellular patches (>8 adjacent cells/patch) that are recognized with an antibody (Pab240) which recognizes mutated but not wild-type p53 protein. These patches...

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Veröffentlicht in:	Carcinogenesis (New York) 2005-08, Vol.26 (8), p.1465-1472
Hauptverfasser:	Lu, Yao-Ping, Lou, You-Rong, Liao, Jie, Xie, Jian-Guo, Peng, Qing-Yun, Yang, Chung S., Conney, Allan H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals Antibody Specificity Biological and medical sciences Caffeine - administration & dosage Caffeine - pharmacology Carcinogenesis, carcinogens and anticarcinogens Epidermis - drug effects Epidermis - pathology Epidermis - radiation effects Immunohistochemistry Medical sciences Mice Mice, Hairless Tea Tumor Suppressor Protein p53 - genetics Tumor Suppressor Protein p53 - radiation effects Tumors Ultraviolet Rays
Online-Zugang:	Volltext
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