Asbestos-induced lung inflammation and epithelial cell proliferation are altered in myeloperoxidase-null mice

Asbestos fibers are carcinogens causing oxidative stress and inflammation, but the sources and ramifications of oxidant production by asbestos are poorly understood. Here, we show that inhaled chrysotile asbestos fibers cause increased myeloperoxidase activity in bronchoalveolar lavage fluids (BALF)...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2005-11, Vol.65 (21), p.9670-9677
Hauptverfasser:	HAEGENS, Astrid, VAN DER VLIET, Albert, MOSSMAN, Brooke T, BUTNOR, Kelly J, HEINTZ, Nicholas, TAATJES, Douglas, HEMENWAY, David, VACEK, Pamela, FREEMAN, Bruce A, HAZEN, Stanley L, BRENNAN, Marie Luise
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Asbestos - toxicity Biological and medical sciences Bronchoalveolar Lavage Fluid Carcinogenesis, carcinogens and anticarcinogens Cell Growth Processes - drug effects Cell Growth Processes - physiology Chemical agents Chemical and industrial products toxicology. Toxic occupational diseases Cyclin D1 - metabolism Epithelial Cells - cytology Epithelial Cells - drug effects Epithelial Cells - enzymology Inhalation Exposure Male Medical sciences Metals and various inorganic compounds Mice Mice, Inbred C57BL Peroxidase - deficiency Peroxidase - metabolism Pneumonia - chemically induced Pneumonia - enzymology Toxicology Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!