Encephalitogenic and tolerogenic potential of altered peptide ligands of MOG and PLP in Biozzi ABH mice

Altered peptide ligands (APL) are highly effective in inhibiting experimental autoimmune encephalomyelitis (EAE) in rodents although clinical trials in multiple sclerosis reveal severe limitations probably due to the diverse and differential effects of APL in vivo compared to in vitro. Myelin oligod...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of neuroimmunology 2005-10, Vol.167 (1), p.23-33
Hauptverfasser:	Heijmans, Nicole, Smith, Paul A., Morris-Downes, Margaret M., Pryce, Gareth, Baker, David, Donaldson, Anna V.J., 't Hart, Bert, Amor, Sandra
Format:	Artikel
Sprache:	eng
Schlagworte:	Altered peptide ligands Amino Acid Sequence Amino Acid Substitution - physiology Animals Cell Proliferation Cytokines - metabolism Disease Models, Animal Encephalomyelitis, Autoimmune, Experimental - chemically induced Encephalomyelitis, Autoimmune, Experimental - immunology Experimental autoimmune encephalomyelitis Freund's Adjuvant Ligands Mice Mice, Biozzi Multiple sclerosis Myelin oligodendrocyte glycoprotein Myelin Proteins Myelin Proteolipid Protein - immunology Myelin-Associated Glycoprotein - immunology Nerve Tissue Proteins - immunology Peptides - pharmacology Statistics, Nonparametric T-Lymphocytes - immunology Time Factors Tolerance
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!