Protein kinase B is required for follicle-stimulating hormone mediated beta-catenin accumulation and estradiol production in granulosa cells of cattle

Follicle-stimulating hormone regulation of ovarian estradiol (E2) production requires involvement of beta-catenin (CTNNB1), a transcriptional co-factor. In cultured granulosa cells (GC) of cattle, FSH treatment increased protein abundance of CTNNB1 as well as protein kinase B (AKT), a molecule known...

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Veröffentlicht in:Animal reproduction science 2015-12, Vol.163, p.97-104
Hauptverfasser: Gómez, B.I., Gifford, C.A., Hallford, D.M., Hernandez Gifford, J.A.
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Sprache:eng
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