Outcome of relapsing Clostridium difficile infections do not correlate with virulence-, spore- and vegetative cell-associated phenotypes

One of the main clinical challenges of Clostridium difficile infections (CDI) is the high rate of relapse episodes. The main determinants involved in relapse of CDI include the presence of antibiotic-resistant C. difficile spores in the colonic environment and a permanent state of dysbiosis of the m...

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Veröffentlicht in:	Anaerobe 2015-12, Vol.36, p.30-38
Hauptverfasser:	Plaza-Garrido, Ángela, Miranda-Cárdenas, Camila, Castro-Córdova, Pablo, Olguín-Araneda, Valeria, Cofré-Araneda, Glenda, Hernández-Rocha, Cristian, Carman, Robert, Ibáñez, Patricio, Fawley, Warren N., Wilcox, Mark H., Gil, Fernando, Calderón, Iván L., Fuentes, Juan A., Guzmán-Durán, Ana María, Alvarez-Lobos, Manuel, Paredes-Sabja, Daniel
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Bacterial Proteins - genetics Bacterial Proteins - metabolism Biofilm Biofilms Caco-2 Cells Clostridium difficile Clostridium difficile - genetics Clostridium difficile - isolation & purification Clostridium difficile - pathogenicity Clostridium difficile - physiology Clostridium Infections - microbiology Clostridium Infections - pathology Cohort Studies Drug Resistance, Bacterial Humans Phenotype Recurrence Recurrent CDI Relapse Relapsing CDI Spore adherence Spore germination Spores, Bacterial - genetics Spores, Bacterial - growth & development Spores, Bacterial - metabolism Spores, Bacterial - pathogenicity Sporulation Virulence
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