Phosphatase regulation of macrophage activation
Highlights • The lipid phosphatases SHIP and PTEN negatively regulate M(IL-4) activation. • The protein tyrosine phosphatase (PTP) SHP-2 negatively regulates M(IL-4) activation. • The PTP PTPN22 and the protein phosphatase MKP-1 negatively regulate M(IFNγ) activation. • The PTPs PTP1B and SHP-1 nega...
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| Veröffentlicht in: | Seminars in immunology 2015-08, Vol.27 (4), p.276-285 |
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| container_title | Seminars in immunology |
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| creator | Kozicky, Lisa K Sly, Laura M |
| description | Highlights • The lipid phosphatases SHIP and PTEN negatively regulate M(IL-4) activation. • The protein tyrosine phosphatase (PTP) SHP-2 negatively regulates M(IL-4) activation. • The PTP PTPN22 and the protein phosphatase MKP-1 negatively regulate M(IFNγ) activation. • The PTPs PTP1B and SHP-1 negatively regulate M(LPS) activation. |
| doi_str_mv | 10.1016/j.smim.2015.07.001 |
| format | Article |
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| ispartof | Seminars in immunology, 2015-08, Vol.27 (4), p.276-285 |
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Allergy and Immunology Animals Humans Lipid phosphatase Macrophage Activation Macrophages - cytology Macrophages - enzymology Macrophages - immunology MKP-1 Phosphoric Monoester Hydrolases - metabolism Protein phosphatase Protein tyrosine phosphatase Protein Tyrosine Phosphatases - metabolism PTEN PTP1B PTPN22 SHIP SHP-1 Shp2 |
| title | Phosphatase regulation of macrophage activation |
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