Immune function of C1q and its modulators CD91 and CD93

C1q is a subcomponent of the first component of complement C1, which is a multimolecular complex comprising one molecule of C1q and two molecules each of the autoreactive proteases, C1r and C1s. This multimolecular complex triggers the classical pathway of complement. Advances in the past several ye...

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Veröffentlicht in:	Critical Reviews in Immunology 2005, Vol.25 (4), p.305-330
Hauptverfasser:	Tarr, Joanna, Eggleton, Paul
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, CD - physiology Apoptosis - physiology Complement C1q - metabolism Complement C1q - physiology Humans Immunity, Innate Low Density Lipoprotein Receptor-Related Protein-1 Membrane Glycoproteins - physiology Membrane Glycoproteins - ultrastructure Phagocytosis - physiology Receptors, Complement - physiology Receptors, Complement - ultrastructure
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