Perchlorate Affects Thyroid Function in Eastern Mosquitofish (Gambusia holbrooki) at Environmentally Relevant Concentrations

The purpose of this study was to determine the effects of perchlorate on thyroid function in mosquitofish. Adult mosquitofish were exposed to 0, 0.1, 1, 10, 100, and 1000 mg/L sodium perchlorate for 2, 10, and 30 d. Whole body thyroxin (T4) content and histological assessment of thyroid follicles (e...

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Veröffentlicht in:	Environmental science & technology 2005-07, Vol.39 (14), p.5190-5195
Hauptverfasser:	Bradford, Carrie M, Rinchard, Jacques, Carr, James A, Theodorakis, Christopher
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal, plant and microbial ecology Animals Applied ecology Biological and medical sciences Biomarkers - blood Chemical compounds Contamination Culicidae Cyprinodontiformes - physiology Dose-Response Relationship, Drug Ecotoxicology, biological effects of pollution Effects of pollution and side effects of pesticides on protozoa and invertebrates Environmental impact Female Fish Fundamental and applied biological sciences. Psychology Gambusia holbrooki Histopathology Hyperplasia Perchlorates - toxicity Sensitivity and Specificity Thyroid gland Thyroid Gland - drug effects Thyroid Gland - pathology Thyroid Gland - physiology Thyroxine - blood Water pollution
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