Dynamic Regulation of Delta-Opioid Receptor in Rat Trigeminal Ganglion Neurons by Lipopolysaccharide-induced Acute Pulpitis

Abstract Introduction Delta-opioid receptor (DOR) and its endogenous ligands distribute in trigeminal system and play a very important role in modulating peripheral inflammatory pain. DOR activation can trigger p44/42 mitogen-activated protein kinase (ERK1/2) and Akt signaling pathways, which partic...

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Veröffentlicht in:	Journal of endodontics 2015-12, Vol.41 (12), p.2014-2020
Hauptverfasser:	Huang, Jin, BMed, Lv, Yiheng, BMed, Fu, Yunjie, MMed, Ren, Lili, MMed, Wang, Pan, MMed, Liu, Baozhu, BMed, Huang, Keqiang, MMed, Bi, Jing, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute pulpitis Animals Dentistry Disease Models, Animal Endocrinology & Metabolism Immunohistochemistry Lipopolysaccharides Male Neurons - metabolism pAkt (Ser473) pERK1/2 Pulpitis - chemically induced Pulpitis - metabolism Pulpitis - pathology rat Rats, Sprague-Dawley Receptors, Opioid, delta - metabolism Signal Transduction trigeminal ganglion Trigeminal Ganglion - metabolism δ-opioid receptor
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