Nerve growth factor-induced circadian phase shifts and MAP kinase activation in the hamster suprachiasmatic nuclei

Circadian rhythms are entrained by light and by several neurochemical stimuli. In hamsters housed in constant darkness, i.c.v. administration of nerve growth factor (NGF) at various times in their circadian cycle produced phase shifts of locomotor activity rhythms that were similar in direction and...

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Veröffentlicht in:	The European journal of neuroscience 2005-08, Vol.22 (3), p.665-671
Hauptverfasser:	Pizzio, Gastón A., Hainich, Ernesto C., Plano, Santiago A., Ralph, Martin R., Golombek, Diego A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Animals Behavior, Animal - drug effects Blotting, Western - methods Cell Count - methods circadian rhythm Circadian Rhythm - drug effects Cricetinae Dizocilpine Maleate - pharmacology Drug Interactions entrainment Enzyme Activation - drug effects ERK1/2 Excitatory Amino Acid Antagonists - pharmacology FOS Gene Expression Regulation - drug effects Gene Expression Regulation - physiology Gene Expression Regulation - radiation effects Immunohistochemistry - methods Light Male MAPK Mesocricetus auratus Mitogen-Activated Protein Kinase 3 - metabolism Mitogen-Activated Protein Kinases - metabolism MK801 Motor Activity - drug effects Nerve Growth Factor - pharmacology NGF Phosphorylation - drug effects Proto-Oncogene Proteins c-fos - metabolism Suprachiasmatic Nucleus - drug effects Suprachiasmatic Nucleus - metabolism Time Factors
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