Total Synthesis of Bioactive Tricyclic Marine Alkaloids, Lepadiformine and Related Compounds

The first total synthesis of tricyclic marine alkaloids (±)-fasicularin (2) and (±)-lepadiformine (5) has been accomplished. The key common strategic element for the synthesis is the stereocontrolled intramolecular hetero-Diels–Alder reaction of an N-acylnitroso moiety with an exocyclic diene with o...

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Veröffentlicht in:Bulletin of the Chemical Society of Japan 2003-11, Vol.76 (11), p.2059-2074
Hauptverfasser: Kibayashi, Chihiro, Aoyagi, Sakae, Abe, Hideki
Format: Artikel
Sprache:eng
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