Changes of fermentation pathways of fecal microbial communities associated with a drug treatment that increases dietary starch in the human colon

Acarbose inhibits starch digestion in the human small intestine. This increases the amount of starch available for microbial fermentation to acetate, propionate, and butyrate in the colon. Relatively large amounts of butyrate are produced from starch by colonic microbes. Colonic epithelial cells use...

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Veröffentlicht in:	Applied and Environmental Microbiology 1999-07, Vol.65 (7), p.2807-2812
Hauptverfasser:	Wolin, M.J, Miller, T.L, Yerry, S, Zhang, Y, Bank, S, Weaver, G.A
Format:	Artikel
Sprache:	eng
Schlagworte:	Acarbose Acetates - metabolism Adult Animal, plant and microbial ecology Bacteria - metabolism Biological and medical sciences Butyrates - metabolism Carbohydrates Carbon Dioxide - metabolism Colon Colon - metabolism Colon - microbiology Cross-Over Studies Dietary Carbohydrates - administration & dosage Dietary Carbohydrates - metabolism Drug therapy Feces Feces - microbiology Fermentation Fundamental and applied biological sciences. Psychology Gas Chromatography-Mass Spectrometry Glucose - metabolism Humans intestinal microorganisms Magnetic Resonance Spectroscopy Microbial ecology Microbiology Normal microflora of man and animals. Rumen Physiology and Biotechnology Propionates - metabolism Starch - administration & dosage Starch - metabolism Trisaccharides - metabolism Trisaccharides - pharmacology
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