Identification of Elaiophylin Skeletal Variants from the Indonesian Streptomyces sp. ICBB 9297

Four new elaiophylin macrolides (1–4), together with five known elaiophylins (5–9), have been isolated from cultures of the Indonesian soil bacterium Streptomyces sp. ICBB 9297. The new compounds have macrocyclic skeletons distinct from those of the known dimeric elaiophylins in that one or both of...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2015-11, Vol.78 (11), p.2768-2775
Hauptverfasser:	Sheng, Yan, Lam, Phillip W, Shahab, Salmah, Santosa, Dwi Andreas, Proteau, Philip J, Zabriskie, T. Mark, Mahmud, Taifo
Format:	Artikel
Sprache:	eng
Schlagworte:	Acyl Coenzyme A - metabolism Acyltransferases - metabolism Anti-Bacterial Agents - chemistry Catalytic Domain Indonesia Macrolides - chemistry Macrolides - isolation & purification Microbial Sensitivity Tests Molecular Structure Mycobacterium smegmatis - drug effects Polyketide Synthases - metabolism Soil Microbiology Streptomyces - chemistry
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