Editor's Choice – First Results of the Covered Endovascular Reconstruction of the Aortic Bifurcation (CERAB) Technique for Aortoiliac Occlusive Disease

Objective In this study the first results are presented of a new endovascular technique using covered stents to reconstruct the aortic bifurcation in patients with aortoiliac occlusive disease. With the “Covered Endovascular Reconstruction of the Aortic Bifurcation” (CERAB) technique, the anatomy an...

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Veröffentlicht in:European journal of vascular and endovascular surgery 2015-11, Vol.50 (5), p.638-647
Hauptverfasser: Grimme, F.A.B, Goverde, P.C.J.M, Verbruggen, P.J.E.M, Zeebregts, C.J, Reijnen, M.M.P.J
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container_end_page 647
container_issue 5
container_start_page 638
container_title European journal of vascular and endovascular surgery
container_volume 50
creator Grimme, F.A.B
Goverde, P.C.J.M
Verbruggen, P.J.E.M
Zeebregts, C.J
Reijnen, M.M.P.J
description Objective In this study the first results are presented of a new endovascular technique using covered stents to reconstruct the aortic bifurcation in patients with aortoiliac occlusive disease. With the “Covered Endovascular Reconstruction of the Aortic Bifurcation” (CERAB) technique, the anatomy and physiology of the aortic bifurcation is mimicked. Material and methods Between 2009 and March 2014, 103 patients (51 male, 52 female) suffering from obstructive lesions at the level of the aortic bifurcation were treated with CERAB in two clinics. The median age was 61 years (range 36–85 years). Lesion morphology was evaluated by CT angiography. Six TASC-II B lesions, nine TASC-II C lesions, and 88 TASC-II D lesions were treated. Follow up was a median 12 months (range 0–49 months) and consisted of clinical examination, ankle brachial indices, and duplex ultrasound examination. Results Technical success was obtained in 98 procedures (95.1%). In five cases lesions could not be recanalized. Primary patency was 87.3% at 1 year and 82.3% at 2 years, while secondary patency was 95.0% at 1 year and 95.0% at 2 years. Mean ankle brachial indices improved significantly from 0.64 ± 0.21 before to 0.91 ± 014, after the procedure ( p  
doi_str_mv 10.1016/j.ejvs.2015.06.112
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With the “Covered Endovascular Reconstruction of the Aortic Bifurcation” (CERAB) technique, the anatomy and physiology of the aortic bifurcation is mimicked. Material and methods Between 2009 and March 2014, 103 patients (51 male, 52 female) suffering from obstructive lesions at the level of the aortic bifurcation were treated with CERAB in two clinics. The median age was 61 years (range 36–85 years). Lesion morphology was evaluated by CT angiography. Six TASC-II B lesions, nine TASC-II C lesions, and 88 TASC-II D lesions were treated. Follow up was a median 12 months (range 0–49 months) and consisted of clinical examination, ankle brachial indices, and duplex ultrasound examination. Results Technical success was obtained in 98 procedures (95.1%). In five cases lesions could not be recanalized. Primary patency was 87.3% at 1 year and 82.3% at 2 years, while secondary patency was 95.0% at 1 year and 95.0% at 2 years. Mean ankle brachial indices improved significantly from 0.64 ± 0.21 before to 0.91 ± 014, after the procedure ( p  &lt; .001). The overall 30 day complication rate was 23.3%, including 22 minor complications and two major complications (1.9%). There was no 30 day mortality. Median hospital stay was 2 days (range 1–16 days). Conclusions The CERAB technique appears to be a safe and feasible alternative to open surgical reconstruction of the aortic bifurcation in complex occlusive disease. Comparative studies with the current gold standards are indicated.</description><identifier>ISSN: 1078-5884</identifier><identifier>EISSN: 1532-2165</identifier><identifier>DOI: 10.1016/j.ejvs.2015.06.112</identifier><identifier>PMID: 26343310</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Aorta, Abdominal - surgery ; Aortic bifurcation ; Aortoiliac ; Arterial occlusive disease ; Arterial Occlusive Diseases - surgery ; CERAB ; Covered stents ; Endovascular Procedures - methods ; Female ; Humans ; Iliac Artery - surgery ; Male ; Middle Aged ; Peripheral vascular disease ; Retrospective Studies ; Stents ; Surgery</subject><ispartof>European journal of vascular and endovascular surgery, 2015-11, Vol.50 (5), p.638-647</ispartof><rights>European Society for Vascular Surgery</rights><rights>2015 European Society for Vascular Surgery</rights><rights>Copyright © 2015 European Society for Vascular Surgery. 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All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c521t-293a91576fbf5e547bbe2cb049cd92c84d93843fcc2135d17881fda142ebba9f3</citedby><cites>FETCH-LOGICAL-c521t-293a91576fbf5e547bbe2cb049cd92c84d93843fcc2135d17881fda142ebba9f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1078588415005407$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26343310$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Grimme, F.A.B</creatorcontrib><creatorcontrib>Goverde, P.C.J.M</creatorcontrib><creatorcontrib>Verbruggen, P.J.E.M</creatorcontrib><creatorcontrib>Zeebregts, C.J</creatorcontrib><creatorcontrib>Reijnen, M.M.P.J</creatorcontrib><title>Editor's Choice – First Results of the Covered Endovascular Reconstruction of the Aortic Bifurcation (CERAB) Technique for Aortoiliac Occlusive Disease</title><title>European journal of vascular and endovascular surgery</title><addtitle>Eur J Vasc Endovasc Surg</addtitle><description>Objective In this study the first results are presented of a new endovascular technique using covered stents to reconstruct the aortic bifurcation in patients with aortoiliac occlusive disease. With the “Covered Endovascular Reconstruction of the Aortic Bifurcation” (CERAB) technique, the anatomy and physiology of the aortic bifurcation is mimicked. Material and methods Between 2009 and March 2014, 103 patients (51 male, 52 female) suffering from obstructive lesions at the level of the aortic bifurcation were treated with CERAB in two clinics. The median age was 61 years (range 36–85 years). Lesion morphology was evaluated by CT angiography. Six TASC-II B lesions, nine TASC-II C lesions, and 88 TASC-II D lesions were treated. Follow up was a median 12 months (range 0–49 months) and consisted of clinical examination, ankle brachial indices, and duplex ultrasound examination. Results Technical success was obtained in 98 procedures (95.1%). In five cases lesions could not be recanalized. Primary patency was 87.3% at 1 year and 82.3% at 2 years, while secondary patency was 95.0% at 1 year and 95.0% at 2 years. Mean ankle brachial indices improved significantly from 0.64 ± 0.21 before to 0.91 ± 014, after the procedure ( p  &lt; .001). The overall 30 day complication rate was 23.3%, including 22 minor complications and two major complications (1.9%). There was no 30 day mortality. Median hospital stay was 2 days (range 1–16 days). Conclusions The CERAB technique appears to be a safe and feasible alternative to open surgical reconstruction of the aortic bifurcation in complex occlusive disease. Comparative studies with the current gold standards are indicated.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Aorta, Abdominal - surgery</subject><subject>Aortic bifurcation</subject><subject>Aortoiliac</subject><subject>Arterial occlusive disease</subject><subject>Arterial Occlusive Diseases - surgery</subject><subject>CERAB</subject><subject>Covered stents</subject><subject>Endovascular Procedures - methods</subject><subject>Female</subject><subject>Humans</subject><subject>Iliac Artery - surgery</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Peripheral vascular disease</subject><subject>Retrospective Studies</subject><subject>Stents</subject><subject>Surgery</subject><issn>1078-5884</issn><issn>1532-2165</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9ks1u1DAUhSMEoqXwAiyQd5RFBv_E-ZEQ0nSYAlKlSqWsLefmRuMhExdfZ6TueAdWvB5PgtNpWbBgZUv-zpHvPSfLXgq-EFyUb7cL3O5pIbnQC14uhJCPsmOhlcylKPXjdOdVneu6Lo6yZ0RbzrkWSj_NjmSpCqUEP85-rTsXfXhNbLXxDpD9_vGTnbtAkV0hTUMk5nsWN8hWfo8BO7YeO7-3BNNgQ2LAjxTDBNH58QFd-hAdsDPXTwHs3cvpan21PHvDrhE2o_s-Iet9uAO9G5wFdgkwTOT2yD44Qkv4PHvS24Hwxf15kn09X1-vPuUXlx8_r5YXOWgpYi4bZRuhq7Jve426qNoWJbS8aKBrJNRF16i6UD2ATLN3oqpr0XdWFBLb1ja9OslOD743wad_UTQ7R4DDYEf0ExlRqbKsaqGahMoDCsETBezNTXA7G26N4GaOxGzNHImZIzG8NCmSJHp17z-1O-z-Sh4ySMC7A4Bpyr3DYAgcjoCdCwjRdN793__9P3IY3OjADt_wFmnrpzCm_RlhSBpuvsylmDshdKpDwSv1B6C8tGc</recordid><startdate>20151101</startdate><enddate>20151101</enddate><creator>Grimme, F.A.B</creator><creator>Goverde, P.C.J.M</creator><creator>Verbruggen, P.J.E.M</creator><creator>Zeebregts, C.J</creator><creator>Reijnen, M.M.P.J</creator><general>Elsevier Ltd</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20151101</creationdate><title>Editor's Choice – First Results of the Covered Endovascular Reconstruction of the Aortic Bifurcation (CERAB) Technique for Aortoiliac Occlusive Disease</title><author>Grimme, F.A.B ; Goverde, P.C.J.M ; Verbruggen, P.J.E.M ; Zeebregts, C.J ; Reijnen, M.M.P.J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c521t-293a91576fbf5e547bbe2cb049cd92c84d93843fcc2135d17881fda142ebba9f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Aorta, Abdominal - surgery</topic><topic>Aortic bifurcation</topic><topic>Aortoiliac</topic><topic>Arterial occlusive disease</topic><topic>Arterial Occlusive Diseases - surgery</topic><topic>CERAB</topic><topic>Covered stents</topic><topic>Endovascular Procedures - methods</topic><topic>Female</topic><topic>Humans</topic><topic>Iliac Artery - surgery</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Peripheral vascular disease</topic><topic>Retrospective Studies</topic><topic>Stents</topic><topic>Surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Grimme, F.A.B</creatorcontrib><creatorcontrib>Goverde, P.C.J.M</creatorcontrib><creatorcontrib>Verbruggen, P.J.E.M</creatorcontrib><creatorcontrib>Zeebregts, C.J</creatorcontrib><creatorcontrib>Reijnen, M.M.P.J</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of vascular and endovascular surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Grimme, F.A.B</au><au>Goverde, P.C.J.M</au><au>Verbruggen, P.J.E.M</au><au>Zeebregts, C.J</au><au>Reijnen, M.M.P.J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Editor's Choice – First Results of the Covered Endovascular Reconstruction of the Aortic Bifurcation (CERAB) Technique for Aortoiliac Occlusive Disease</atitle><jtitle>European journal of vascular and endovascular surgery</jtitle><addtitle>Eur J Vasc Endovasc Surg</addtitle><date>2015-11-01</date><risdate>2015</risdate><volume>50</volume><issue>5</issue><spage>638</spage><epage>647</epage><pages>638-647</pages><issn>1078-5884</issn><eissn>1532-2165</eissn><abstract>Objective In this study the first results are presented of a new endovascular technique using covered stents to reconstruct the aortic bifurcation in patients with aortoiliac occlusive disease. With the “Covered Endovascular Reconstruction of the Aortic Bifurcation” (CERAB) technique, the anatomy and physiology of the aortic bifurcation is mimicked. Material and methods Between 2009 and March 2014, 103 patients (51 male, 52 female) suffering from obstructive lesions at the level of the aortic bifurcation were treated with CERAB in two clinics. The median age was 61 years (range 36–85 years). Lesion morphology was evaluated by CT angiography. Six TASC-II B lesions, nine TASC-II C lesions, and 88 TASC-II D lesions were treated. Follow up was a median 12 months (range 0–49 months) and consisted of clinical examination, ankle brachial indices, and duplex ultrasound examination. Results Technical success was obtained in 98 procedures (95.1%). In five cases lesions could not be recanalized. Primary patency was 87.3% at 1 year and 82.3% at 2 years, while secondary patency was 95.0% at 1 year and 95.0% at 2 years. Mean ankle brachial indices improved significantly from 0.64 ± 0.21 before to 0.91 ± 014, after the procedure ( p  &lt; .001). The overall 30 day complication rate was 23.3%, including 22 minor complications and two major complications (1.9%). There was no 30 day mortality. Median hospital stay was 2 days (range 1–16 days). Conclusions The CERAB technique appears to be a safe and feasible alternative to open surgical reconstruction of the aortic bifurcation in complex occlusive disease. Comparative studies with the current gold standards are indicated.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>26343310</pmid><doi>10.1016/j.ejvs.2015.06.112</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record>
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subjects Adult
Aged
Aged, 80 and over
Aorta, Abdominal - surgery
Aortic bifurcation
Aortoiliac
Arterial occlusive disease
Arterial Occlusive Diseases - surgery
CERAB
Covered stents
Endovascular Procedures - methods
Female
Humans
Iliac Artery - surgery
Male
Middle Aged
Peripheral vascular disease
Retrospective Studies
Stents
Surgery
title Editor's Choice – First Results of the Covered Endovascular Reconstruction of the Aortic Bifurcation (CERAB) Technique for Aortoiliac Occlusive Disease
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