Solanocapsine derivatives as potential inhibitors of acetylcholinesterase: Synthesis, molecular docking and biological studies

[Display omitted] •Solanocapsine, a steroidal alkaloid was isolated from Solanum pseudocapsicum L.•A set of solanocapsine chemical derivatives was prepared.•Acetylcholinesterase inhibitory activity of all compounds was examined.•Some structure–activity relationships were established.•Interactions wi...

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Veröffentlicht in:Steroids 2015-12, Vol.104, p.95-110
Hauptverfasser: García, Manuela E., Borioni, José L., Cavallaro, Valeria, Puiatti, Marcelo, Pierini, Adriana B., Murray, Ana P., Peñéñory, Alicia B.
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Sprache:eng
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